He forced Ospina into a save with his left-foot curler from the right but then picked out fellow substitute Antony with a perfect in-swinging delivery, only for Ospina to make a brilliant reaction save from point-blank range.
Neymar was at the heart of much of Brazil's attacks but when he teed up a teammate on the edge of the area, it was defensive midfielder Fred who appeared on the scene, and it was no surprise to see him blaze over the bar from 18 yards.
Ramiro Vaca's goal eight minutes from time gave Bolivia victory despite having fellow substitute Henry Vaca sent off on 75 minutes.
Brazil started brightly and dominated the opening quarter as Neymar thrashed a fierce drive that forced David Ospina into a diving parry at his near post.
Colombia grew more adventurous in the second half and Brazil goalkeeper Alisson tipped a fierce Mateus Uribe drive from distance over the bar..Read Full Story